What chemical is associated with pain and can be found around trigger points?

The chemical associated with pain that can be found around trigger points is Calcitonin Gene-Related Peptide (CGRP). CGRP is a neuropeptide that plays a significant role in the transmission of pain signals and is involved in the inflammatory response. When muscle tissue becomes irritated or develops trigger points, such as in myofascial pain syndrome, CGRP levels increase in the affected area. This can lead to heightened pain sensitivity and a greater perception of discomfort.

CGRP is released from sensory neurons and contributes to the vasodilation and neurogenic inflammation that often accompany pain pathology. In terms of dry needling, understanding the presence of CGRP at trigger points is essential for addressing pain effectively and facilitating healing in the targeted muscular regions. This knowledge can guide practitioners in their approach to treatment, making it essential for those working in the field of pain management and rehabilitation.